Alexandra Chabrerie1,3 -
Fatma Ozlen1,3 -
Shin Nakajima1,3 -
Michael Leventon2 -
Hideki Atsumi1 -
Eric Grimson2 -
Erwin Keeve1 -
Sandra Helmers4 -
James Riviello Jr.4 -
Gregory Holmes4 -
Frank Duffy4 -
Ferenc Jolesz1 -
Ron Kikinis1 -
Peter Black3
1
Surgical Planning Laboratory, Brigham and Women's
Hospital,
Harvard Medical School, Boston, MA
2
Artificial Intelligence Laboratory,
Massachusetts
Institute of Technology, Cambridge, MA
3
Division of Neurosurgery, Brigham and Women's
Hospital, Children's Hospital, Harvard Medical School, Boston, MA
4
Department of Neurology, Children's Hospital,
Harvard
Medical School, Boston, MA
We have used MRI-based three-dimensional (3D) reconstruction and a real-time, frameless, stereotactic navigation device to facilitate the removal of seizure foci in children suffering from intractable epilepsy. Using this system, the location of subdural grid and strip electrodes is recorded on the 3D model to facilitate focus localization and resection. Ten operations were performed - two girls and eight boys ranging in age from 3-17 - during which 3D reconstruction and surgical instrument tracking navigation was used. In all cases, the patients tolerated the procedure well and showed no post-operative neurological deficits.